Emendo was set up to expand what is possible in genome editing. We believe that challenges can be overcome by fusing expertise in diverse disciplines, and by looking at the core questions with a new approach. Having studied at top academic institutions, including the Weizmann Institute, Emendo’s founders came together to pool their collective knowledge of protein engineering and DNA repair to achieve a shared goal: the creation of genetic medicines that deliver on the promise of gene editing. By transforming the available tools, we are able to address those disorders and diseases that are currently considered to be untreatable. Working at the cutting edge of gene editing, the Emendo team combines knowledge, expertise and proven scientific methodologies, with creativity, ingenuity and daring to push the boundaries and achieve more.
Board Of Directors
Stephen Squinto, Ph.D.
Stephen Squinto is a Venture Partner with OrbiMed who brings over 25 years of biotechnology industry experience. Dr. Squinto was a co-founder of Alexion Pharmaceuticals, Inc. and recently served as its Executive Vice President and Chief Global Operations Officer.
Member Of The Board
Erez Chimovits is a Senior Managing Director in Orbimed. Erez has 14 years of operational experience, including 10 years of senior managerial experience in public companies. Prior to joining OrbiMed Erez was the CEO of NasVax (TASE:NSVX).
Member Of The Board
Michal Silverberg joined TVI in September 2014 as Senior Director for External Innovation with a primary focus on Israel and Europe. Since 1998, she has held positions in various sectors of the life science industry including in the Office of the Chief Scientist of Israel (The Incubator program),
David Baram, Ph.D.
CEO & Member Of The Board
David has 10 years’ experience as an executive manager and entrepreneur. Former managing partner of Base Investments for the past five years, he has brought more than 20 products to market in the healthcare and cosmetics industries.
Co-founder & Member Of The Board
Shilo has 15 years of experience in several management positions in the health industry, spanning the establishment and management of startups from the very initial stages, including business development and fundraising. Amongst these companies, Shilo was co-founder of LabStyle Innovation, where he served as President and COO. He was responsible for propelling the company’s flagship product “Dario” from inception to reality and led the company’s evolution to a public American company (OTC).
David Baram, Ph. D.
David has 10 years’ experience as an executive manager and entrepreneur. Former managing partner of Base Investments for the past five years, he has brought more than 20 products to market in the healthcare and cosmetics industries. Co-founder and member of the board of five biomed companies, inventor of drug development, discovery and delivery methodologies, David holds a PhD and MSc in Structural Biology from the Weizmann Institute of Science. He conducted his research under the Nobel Laureate Professor Ada Yonath.
Lior Izhar, Ph. D.
With over 10 years of research experience in the field of DNA damage and repair, Lior holds a PhD in molecular biology from the Weizmann Institute of Science prior to joining Emendo, he completed his postdoctoral fellowship at the Steve Elledge Lab at Harvard Medical School, where he studied the cellular mechanism responsible for sensing DNA damage and promoting its repair in human cells. Lior brings extensive experience in development and implementation of high resolution as well as screen-oriented assays for DNA repair, including homologous recombination, non-homologous end joining, protein stability, protein localization and small molecule inhibitor sensitization to DNA damage.
VP Intellectual Property & Strategy
Rachel has extensive experience in constructing IP strategy that is designed to serve business objectives, based on careful competitive landscaping, in order to reduce risks and maximize value. Rachel served as IP Director of the technology transfer company of Sheba Medical Center, and later as Director of IP in BASE-Investments. She has managed large consulting projects for international entities such as the EPO, OECD, World Bank, UN and global pharmaceutical companies in the area of global IP policy. In the private market, Rachel has provided in-house support for many biotechnology and medical device companies, and accumulated extensive expertise in IP mining, strategic portfolio design, and hands-on portfolio management. Rachel holds an MSc in Neurobiology from the Weizmann Institute of Science, and a Biotechnology Engineering degree from the Technion, Israel Institute of Technology.
Asael Herman, Ph.D
Joined Emendo as Director of Protein Engineering and in April 2017 appointed as our VP of R&D. Dr. Herman has over 20 years of experience in protein engineering and is an expert in the directed molecular evolution approach. Prior to joining Emendo he led the R&D of Smartzyme Biopharma. He formerly was the VP of R&D at Biolojic Design, an antibodies engineering company. Prior to that he served as Head of Enzyme Engineering at Bio Architecture Lab, a start-up synthetic biology and biofuels firm. Dr. Herman holds a PhD in Bio chemistry and Molecular Biology from the Hebrew University and further trained in protein engineering with Prof. Dan Tawfik at the Weizmann Institute and Prof. Larry Loeb at the University of Washington.
Rafi Emmanuel, Ph.D.
Has over 10 years of research experience in the field of transcription and translation regulation of genes, holds a PhD in molecular biology from the Weizmann Institute of Science, Israel. The research was conducted under the supervision of Prof. Rivka Dikstein. Completed his postdoctoral training at Tel Aviv University at Prof. Dan Peer ‘s laboratory where he developed liposomes-based vehicles for targeted delivery of siRNAs and small molecules. Prior to joining Emendo, he was a senior intern at the Weizmann Institute of Science at the laboratory of Prof. Yardena Samuels, where he established tools for homologous recombination-mediated endogenous epitope tagging using rAAV constructs for studying the function of driver mutations in melanoma. Rafi brings broad experience in the development of constructs for improved gene expression and in the use of viral- and liposomes-based systems for the delivery of nucleic acids.
Lior Zangi, Ph.D.
Scientific Advisory Board Member
Lior is an assistant professor at the Icahn School of Medicine at Mount Sinai, New York. He completed his education and training at the Weizmann Institute of Science and at Harvard University. He has established a new method, mRNA based, for gene delivery to promote cardiovascular regeneration. Currently, Dr. Zangi’s laboratory investigates cellular and organ level regenerative mechanisms that can contribute to new therapeutic approaches to repair and regenerate the heart following myocardial infarction.
Noam Diamant, Ph.D.
Scientific Advisory Board Member
Noam Diamant is biomed professional combining strong academic background with industry R&D experience and deep understanding of intellectual property. Noam received his Ph.D. in the field of DNA damage repair from the Weizmann institute of Science in 2008. His academic research was published in high profile peer-reviewed journals.